WebCHIR-99021 (CT99021) (CHIR-99021) is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. CHIR-99021 (CT99021) shows >500-fold selectivity for GSK … WebDec 29, 2016 · Laduviglusib (CHIR-99021) monohydrochloride is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib monohydrochloride …
Laduviglusib monohydrochloride (CHIR-99021 …
WebLaduviglusib (CHIR-99021) is a potent, selective and orally active GSK-3α/β inhibitor with IC50 s of 10 nM and 6.7 nM. Laduviglusib shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib is also a potent Wnt/β-catenin signaling pathway activator. WebCHIR-99021 (CT99021) is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. CHIR-99021 shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and … inbound recrutement
Laduviglusib (CHIR-99021) GSK-3 阻害剤 MedChemExpress
WebCHIR 99021 is a potent and highly selective inhibitor of glycogen synthase kinase 3 (GSK-3) (IC 50 values are 6.7 and 10 nM for GSK-3β and GSK-3α respectively). Acts as Wnt … WebSynonyms: CHIR 99021 CHIR-99021 CHIR99021 CT-99021 CT99021 Compound class: Synthetic organic Comment: Laduviglusib (CHIR-99021) is an ATP-competitive inhibitor of glycogen synthase kinase-3α and β (GSK-3α/β), equipotent at both isozymes . The chemical structure of CHIR-99021 matches that submitted to the WHO for the INN … WebCHIR-99021 is a highly specific glycogen synthase kinase-3 (GSK-3) inhibitor which can inhibit both isoforms with IC50 of 10 nM (GSK-3α) and 6.7 nM (GSK-3β). CHIR-99021 … inbound recruiting c\u0027est quoi