Irf2bp2 cancer

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August undefined, 2024

WebMar 21, 2024 · IRF2BP2 (Interferon Regulatory Factor 2 Binding Protein 2) is a Protein Coding gene. Diseases associated with IRF2BP2 include Immunodeficiency, Common … WebApr 25, 2024 · The IRF2BP2 (IFN regulatory factor 2 binding protein 2) protein was identified as a nuclear protein that interacts with IFN regulatory factor 2 (IRF-2) and is an IRF-2 …

IRF2BP2: A new player in the regulation of cell homeostasis

WebMay 19, 2016 · The IRF2BP2–CDX-1 fusion gene has been reported in mesenchymal chondrosarcoma, 16 and there is one previous report of IRF2BP2–RARA in APL. 10 Yin et al. 10 reported a case of APL with IRF2BP2–RARA that involved exon 2 of IRF2BP2 and intron 2 of RARA, with breakpoints at positions 1687 bp in IRF2BP2 and 41620 bp in RARA. The … WebSep 25, 2015 · IRF2BP2 is required for the expression of the anti-inflammatory transcription factor Krüppel-like factor 2 (KLF2). Restoring KLF2 in IRF2BP2-deficient macrophages … easley high school logo

The novel tumor suppressor IRF2BP2 regulates Hippo pathway

WebIRF2BP2 INFORMATION. Proteini. Full gene name according to HGNC. Interferon regulatory factor 2 binding protein 2. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. IRF2BP2 (IRF-2BP2) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). WebIRF2BP2-NTRK1 Fusion is present in 0.02% of AACR GENIE cases, with sarcoma, NOS, breast invasive ductal carcinoma, gastric adenocarcinoma, lung adenocarcinoma, and … easley high school football schedule 2022

Unleashing Cell-Intrinsic Inflammation as a Strategy to Kill AML …

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WebSep 25, 2015 · In a recent issue of Circulation Research, Chen et al report that IRF 2–binding protein 2 (IRF2BP2) is a novel regulator of macrophage inflammation and lipid homeostasis that acts by maintaining anti-inflammatory transcription factor Krüppel-like factor 2 (KLF2) expression, therefore reducing susceptibility to atherosclerosis 6 ( Figure 2 ). WebNov 22, 2016 · IRF2BP2 is a downstream target of p53 and repressor of the cell cycle regulator NFAT1 (refs 7, 8). IRF2BP2 is fused to CDX1 as a result of the t (1;5) (q42;q32) … easley high school guidance counselorWebNov 22, 2016 · IRF2BP2 is a downstream target of p53 and repressor of the cell cycle regulator NFAT1 (refs 7, 8). IRF2BP2 is fused to CDX1 as a result of the t (1;5) (q42;q32) in mesenchymal chondrosarcoma... easley home educators

"WebExpression of IRF2BP2 (IRF-2BP2) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. ... To access cancer specific RNA and … " - Irf2bp2 cancer

Irf2bp2 cancer

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WebApr 29, 2024 · The IRF2BP2 protein is found in different organisms and has been described as ubiquitously expressed in normal and tumor cells and tissues, indicating a possible role for this transcriptional... WebMar 29, 2024 · IRF2BP2 is a novel ischemia-induced coactivator of VEGFA expression that may contribute to revascularization of ischemic cardiac and skeletal muscles. IRF2BP2 …

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WebInterferon regulatory factor 2 binding protein 2 is a protein that in humans is encoded by the IRF2BP2 gene. Function. This gene encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Alternative splicing results in multiple transcript variants encoding ... http://english.cemcs.cas.cn/news/202411/t20241120_252214.html

WebJul 29, 2024 · Program of Immunology and Tumor Biology, Brazilian National Cancer Institute (INCA), Rio de Janeiro, RJ, Brazil. 2. Division of Signaling and Gene Expression, La … WebSep 20, 2024 · The conserved Hippo pathway regulates organ size, tissue homeostasis, and tumorigenesis. Interferon regulatory factor 2 binding protein 2 (IRF2BP2) was originally …

WebCÁNCER DE PULMÓN El gen ALK (Anaplastic Lymphoma Kinase) y el gen EML4 (Echinoderm microtubule associated protein-like 4) se encuentran situados en el brazo corto del cromosoma 2, separados por 12 megabases de secuencia, y orientados en direcciones opuestas. Se ha descrito recientemente que alrededor del 5% de los carcinomas de … WebExpression of IRF2BP2 (IRF-2BP2) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We use cookies to enhance the usability of …

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WebIRF2BP2 is altered in 0.02% of all cancers with sarcoma, NOS, breast invasive ductal carcinoma, gastric adenocarcinoma, lung adenocarcinoma, and pancreatic acinar cell … easley homepageWebSep 20, 2024 · IRF2BP2 stabilized VGLL4 protein and repressed tumor progression via the inactivation of YAP-TEAD4 complex in liver cancer (41). In contrast, IRF2BP2 repressed … c \u0026 a machine newington ctWebJan 1, 2024 · For example, IRF2BP2 is confirmed to be upregulated in gastric cancer, and its deficiency impedes cell proliferation and epithelial-mesenchymal transition. 42 IRF2BP2 represses liver cancer progression via stabilizing VGLL4 and further enhancing VGLL4’s inhibitory effects on Hippo pathway. 43 In our study, we discovered that IRF2BP2 might … c\u0026a kinder online shopWebJul 31, 2024 · Overall, cases 12 (harboring IRF2BP2-NTRK1 ), 13 ( PPL- NTRK1 ), and 25 ( ETV6-NTRK3) were morphologically similar, composed of lobules of partially fused papillae with scattered glomeruloid... c \u0026 a machining incWebApr 25, 2024 · Abstract. The IRF2BP2 (IFN regulatory factor 2 binding protein 2) protein was identified as a nuclear protein that interacts with IFN regulatory factor 2 (IRF-2 easley high school marching bandWebIRF2BP2 is involved in 1 fusion, with the following gene: CDX1 (1 mutation in 4 samples) Drug sensitivity data Mutations in IRF2BP2 are associated with altered sensitivity to the following 10 drugs: Dactolisib Docetaxel SN-38 Show all See all drug sensitivity data for IRF2BP2. External links easley high school yearbook 2021WebIRF2BP2-NTRK1 Fusion is present in 0.02% of AACR GENIE cases, with sarcoma, NOS, breast invasive ductal carcinoma, gastric adenocarcinoma, lung adenocarcinoma, and pancreatic acinar cell carcinoma having the greatest prevalence [ 4 ]. Top Disease Cases with IRF2BP2-NTRK1 Fusion References 1. c\u0026a meses sin intereses