WebHome AHA/ASA Journals WebPBPK for extrapolation of human PK Pharmaceuticals +simple-frequently inaccurate-predict average parameters-predict only parent compound-data intensive (in vivo PK) Lung Brain Kidney Heart Muscle ... Jones, H., et al., Clinical Pharmacokinetics, 2006. 45(5): p. 511-542. PBPK model refinements Pharmaceuticals Absorption Aqueous solubility PAMPA ...
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