WebMay 2, 2024 · Good separation of the BSA monomer (72 ± 2 kDa) and dimer (136 ± 4 kDa) was also achieved on the AIEX column with a linear gradient of 75–350 mM NaCl (Fig. 2C). WebProduced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply Rabbit monoclonal [EPR2418Y] to IRF3 Suitable for: Flow Cyt (Intra), ICC/IF, WB, IHC-P Knockout validated Reacts with: Mouse, Human Related conjugates and formulations Carrier Free HRP PE You may also be interested in
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WebDec 31, 2013 · 4O91. PubMed Abstract: We developed a pharmacophore model for type II inhibitors that was used to guide the construction of a library of kinase inhibitors. Kinome-wide selectivity profiling of the library resulted in the identification of a series of 4-substituted 1H-pyrrolo [2,3-b]pyridines that exhibited potent inhibitory activity against two ... WebGeneral description. TAK1 is a serine/threonine protein kinase that mediates signaling by TGFβ and morphogenetic protein (BMP). In response to IL-1, TAK1 forms a kinase complex with TAB1 and this complex is required for the activation of nuclear factor kappa B (NfκB). frozen costume for boys
The IKK Complex, a Central Regulator of NF-kB Activation
WebBackground. p38α (SAPK2A) is a member of the p38 MAPK family which are activated by various environmental stresses and proinflammatory cytokines (1). The activation of p38 requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation … WebAs a third component, NEMO (48-kDa; also known as IKKc, IKKAP1 or Fip-3), was identified by complementation of an NF-jB-unresponsive cell line and by sequencing of IKK-associated polypeptides [14,15]. NEMO is a regulatory non-enzymatic scaffold ... TAB1/2 TAK1 binding protein 1/2 TAK1 TGF-b-activated kinase 1 TBK1 TANK-binding kinase 1 … WebCayman Chemical TAK1-TAB1 Fusion (human, recombinant) Item No. 33990 Download Product Insert (PDF) Download Safety Data Sheet (SDS) (PDF) BULK & CUSTOM BOOKMARK 10 µg $424 Contact for status Active • Host: Insect cells • AA: TAK1 (1-303) … frozen corn syrup