The type i interferonopathies: 10 years on
WebOct 20, 2024 · Europe PMC is an archive of life sciences journal literature. WebThe Type I interferonopathies, ten years on. Nat Rev Immunol, 2024 Oct 20. doi: 10.1038/s41577-021-00633-9. Maurano M, Snyder JM, Connelly C, Henao-Mejia J, …
The type i interferonopathies: 10 years on
Did you know?
WebI am a PhD-trained biologist with over 6 years of work experience in organoid technology, intestinal inflammation, and mucosal immunology. I am particularly interested in studying … WebIn the last ten years, a set of genetic diseases characterized by a defective regulation of type I interferons production, the so-called interferonopathies, were identified, which often showed poor responses to conventional anti-inflammatory drugs, including biologics and glucocorticoids.
WebJan 1, 2024 · AGS is one of a diverse group of conditions classified as type 1 interferonopathies based on evidence of a persistent upregulation of type I interferon signaling. ... Juvenile metachromatic leukodystrophy 10 years post transplant compared with a non-transplanted cohort. Bone Marrow Transplant, 48 (3) (2013), pp. 369-375. WebJan 14, 2024 · Abstract. Type I interferons (IFNs) play a central role in the immune defense against viral infections. Type I IFN activation is induced by pattern-recognition receptors …
WebOct 20, 2024 · Given the common feature of these disorders of an increased type I interferon response, they have often been categorized as 'interferonopathies'. However, this term … WebThe type I interferonopathies: 10 years on. Nature Reviews Immunology 2024-08 Journal article DOI: 10.1038/s41577-021-00633-9 Contributors ... The type I interferonopathies, a conceptual overview. Journal of Experimental Medicine 2016-11-14 …
WebNov 1, 2011 · A few years later, the observation of an improvement in disease status of patients with type I interferonopathies treated by blockers of the type I IFN pathway (i.e., JAK inhibitors) [7] supported ...
WebJun 4, 2016 · Defective regulation of type I interferon response is associated with severe inflammatory phenotypes and autoimmunity. Type I interferonopathies are a clinically … csgoroll calculatorWebIn the last ten years, a set of genetic diseases characterized by a defective regulation of type I interferons production, the so-called interferonopathies, were identified, which often … marche noel 2021 arrasWebOct 30, 2024 · 14.3.5 Autoimmunity. Type I interferonopathies can be associated with autoimmunity, in particular with systemic lupus erythematosus (SLE). SLE was the first … marche nocturne la ciotatWebJun 1, 2024 · Clarifying the molecular anatomy and rate-limiting control points of IRF3-activating systems is not only essential to expand our knowledge of human antiviral immunity and immunization, but it is also a tool for a better understanding of type I interferonopathies given the key role of IRF3 signaling in these diseases [29], [30], [31], [32]. csgoroll cant loginWebIn a landmark review published in Nature Reviews Immunology this week, The type I interferonopathies: 10 years on, Yanick Crow and Dan Stetson (University of Washington) look back at what has been learned since Yanick first coined the term in 2011, and how the field may develop in the years ahead. To mark this milestone, […] marche noel 2021 nordWebFeb 2, 2024 · The expanding phenotype of these diseases is reviewed, highlighting common as well as specific features, and recent advances in the understanding of STING biology … csgoroll cardsWebJun 1, 2024 · Clarifying the molecular anatomy and rate-limiting control points of IRF3-activating systems is not only essential to expand our knowledge of human antiviral … marche noel 2021 colmar